Patch research note: This guide is an original synthesis of public v0.106 patch discussion and community run analysis. It does not copy user posts or screenshots. Start with official context from the Slay the Spire 2 Steam news hub, then compare current community searches such as Chinese v0.106 guide results.
Patch routing is about risk, not trivia
Patch notes matter because they change which risks are real. A new boss pressure point, a reworked enemy, or a shifted relic can make yesterday's greedy path worse. The mistake is reading patch notes like trivia. The useful question is: which route choices should change?
v0.106 discussion has circled around Aeonglass pressure, Infested Prism changes, and whether familiar A10 habits still work. The answer is not to become timid. The answer is to take elites and shops with cleaner reasons.

The new route checklist
Before committing to a risky branch, ask:
| Route Question | Good Signal | Bad Signal |
|---|---|---|
| First elite? | Damage card upgraded or potion ready | Starter deck still doing everything |
| Early shop? | Gold can buy a specific fix | You are shopping without a target |
| Event branch? | Deck already has direction | You still need card rewards |
| Boss path? | Scaling and block both exist | You only solve hallway fights |
This checklist is patch-proof. The exact enemies change, but the logic stays useful.
Aeonglass preparation
Aeonglass-style pressure asks for a deck that does not need four quiet turns. If your plan starts on turn 5, you need enough block, mitigation, or potion value to reach that turn. Do not confuse "my deck scales" with "my deck survives long enough to scale."
The best preparation is balanced:
- One way to reduce or block large incoming turns.
- One scaling plan that starts before the fight is already lost.
- One potion saved for a known dangerous turn.
- Enough draw/filtering to avoid being hostage to the bottom of the deck.
If you lack two of those four, path for safety before the boss.
Infested Prism and elite timing
Infested Prism discussion matters because elite timing is often where runs are won or lost. If the current patch makes certain fights more punishing for slow decks, greedy early elites become worse unless your deck has immediate tools.
Take the elite when your deck has:
- A real damage upgrade.
- A potion that covers the worst enemy pattern.
- A defensive card that prevents one catastrophic turn.
- A route exit if the first elite goes badly.
If you have none of these, the elite is not "high skill." It is gambling.
Shops are fix stations
Patch-sensitive metas make shops more valuable because they can repair a specific hole. Do not enter a shop with the vague idea of buying power. Enter with a target:
| Deck Hole | Shop Target |
|---|---|
| No scaling | Power, relic, or card that wins long fights |
| No block | Defensive card, potion, or relic |
| Bloated deck | Removal |
| Weak elite matchup | Potion plus upgrade route |
If the shop does not offer the target, do not panic-buy a shiny card that creates a new problem.
How to update your old habits
Old habits are useful until the patch exposes them. If you used to take every early elite, keep doing it only when your deck still earns that route. If you used to skip shops until late, consider earlier shops when the patch has made specific fights sharper. If you used to save potions forever, start assigning each potion a job before the fight begins.
Patch-aware play is not about memorizing every number. It is about updating your defaults.
For deeper related pages, read the Aeonglass boss guide, Infested Prism rework guide, and best map pathing strategy.
FAQ
Should I avoid elites after v0.106?
No. Elites are still important. The point is to take them when your deck has the right tools, not because the map offers them.
What is the safest patch-routing habit?
Name the next dangerous fight before choosing a node. If you cannot name what you are preparing for, your route is probably vague.
Are patch guides always temporary?
Specific numbers can change, but route logic, potion planning, and matchup preparation remain useful across patches.
