Bosses4 min read
Boss Preparation Checklist for Slay the Spire 2
A boss preparation checklist for judging damage, block, scaling, potions, upgrades, and route choices before major fights.
bossescheckliststrategyscaling
Boss Hub
Boss prep starts before the boss room
Beat Slay the Spire 2 bosses with matchup guides, final shop planning, potion jobs, scaling checks, and current beta fight notes.
4
Deck Jobs
A10
Risk Level
v0.107.0
Beta Context
Boss Prep
Recommended Path
Start with these guides
Bosses3 min read
Doormaker Boss Guide for Slay the Spire 2
A practical Doormaker boss guide for Slay the Spire 2, covering why the fight is controversial, what deck checks matter, and how to prepare.
doormakerboss-guidecontroversybeta
Bosses3 min read
v0.107 Aeonglass Update Guide
How to re-evaluate Aeonglass after the v0.107.0 Slay the Spire 2 beta discussion, with deck checks, potion jobs, and matchup planning.
v0.107.0aeonglassboss-guidebeta
Bosses6 min read
Aeonglass Boss Guide for Slay the Spire 2 Beta
A patch-aware Aeonglass boss guide covering Wither pressure, setup mistakes, deck requirements, potions, and how to survive the v0.106 beta version.
aeonglassboss-guidewitherbeta-branch
Bosses4 min read
Skulking Colony Fight Guide After v0.106
How to prepare for Skulking Colony in Slay the Spire 2 v0.106.1, including deck checks, potion plans, AoE value, and route decisions.
skulking-colonyv0.106.1fight-guidebosses
Strategy6 min read
Infested Prism Rework Guide: How to Stop Losing Runs
A beta patch guide to the reworked Infested Prism fight, covering skill timing, elite pathing, potion planning, and safer deckbuilding after v0.106.0.
infested-prismelite-guidev0.106.0patch-guide
More Reading
Useful supporting pages
Strategy3 min read
Act 3 Boss Preparation Guide
A late-run Slay the Spire 2 boss preparation guide covering complete win conditions, deck consistency, potion planning, and final shop decisions.
Defense5 min read
Best Defensive Strategy
A Slay the Spire 2 defensive strategy guide for block, weakness, enemy intent, health preservation, and surviving dangerous turns.
Resources4 min read
A10 Potion Planning Guide for v0.106.1
A Slay the Spire 2 A10 beta guide for assigning potion jobs, surviving bad draws, and routing safely after v0.106.1.
Strategy4 min read
v0.106 Aeonglass and Infested Prism Routing Guide
A Slay the Spire 2 v0.106 routing guide for planning elites, shops, potions, and boss prep around Aeonglass pressure and Infested Prism changes.
Heat Checks
Patch rankings and opinionated reviews
Banger
BangerCommunity Split14 Ranked9.2/103 min read
v0.106 Boss Difficulty Ranking: From Free Win to Uninstall
Every boss in Slay the Spire 2 v0.106 ranked by how much they make you want to alt-F4. Spoiler: the community's 'favorite' boss is actually mid.
Banger
BangerCommunity Split15 Ranked9.1/103 min read
v0.106 Build Tier List: Overrated Archetypes That Need to Die
Every major deck archetype in Slay the Spire 2 v0.106 ranked by how well it actually wins runs, survives bad draws, and handles current boss pressure.
Quick Answers
FAQ
Why do strong decks still lose to bosses?
Most boss losses come from missing one deck job: scaling, burst defense, potion coverage, or draw consistency. Boss preparation starts several nodes before the fight.
Which current beta boss should I study first?
Start with Aeonglass and Skulking Colony because they represent the current beta pressure around slow setup, hand quality, and multi-problem turns.