Louse Progenitor in Slay the Spire 2

Slay the Spire 2 Monster

Louse Progenitor

Louse Progenitor is a normal encounter with 134-136 base HP and 138-141 HP at high Ascension. Its documented pattern is Always uses Web Cannon.

Tracked beta change (v0.111.0 beta): Strength gain at Ascension 9 increased from 5 to 7; the lower-difficulty value remains 5. Official sourceThe facts below remain the current main-branch data until this beta is promoted.
Encounter
Normal
Base HP
134-136
High Ascension HP
138-141
Known moves
3
Act
Act 2 - Hive

Moves and intents

MoveIntentDamageBlock
Web CannonAttack + Debuff9 (10 A)-
PounceAttack14 (16 A)-
Curl and GrowDefend + Buff-14

Attack pattern

Always uses Web Cannon

Preparation notes

Use the move table as a damage threshold, not a script that replaces reading the fight. Ascension, multiplayer scaling, powers, and patch changes can alter the exact line. For boss-specific planning, continue to the boss guide hub.

Used in real decisions

Guides that mention Louse Progenitor