Skulking Colony Fight Guide After v0.106
How to prepare for Skulking Colony in Slay the Spire 2 v0.106.1, including deck checks, potion plans, AoE value, and route decisions.
Guide Codex
Find the answer your run needs: current patch strategy, reliable builds, card and relic decisions, boss preparation, and beginner paths.
Current beta · Builds · Bosses · Beginner paths
Current Library
How to prepare for Skulking Colony in Slay the Spire 2 v0.106.1, including deck checks, potion plans, AoE value, and route decisions.
A practical Slay the Spire 2 Ironclad A10 guide for greedy upgrade routes, strength scaling, lethal math, and when a no-rest plan is actually safe.
A Necrobinder A10 guide for Osty summon timing, doom thresholds, control turns, hallway safety, and when to stop adding slow payoff cards.
A Regent A10 strategy guide for forge timing, star setup, Sovereign Blade turns, defensive pacing, and when to delay burst damage.
A Slay the Spire 2 Silent A10 guide for turning zero-cost shivs into a real deck with draw, discard, block, poison pivots, and boss scaling.
A timely viewer guide for the Devour the Tower Slay the Spire 2 tournament, covering what to watch for in routes, boss prep, character picks, and beta patch strategy.
A beta patch guide to the reworked Infested Prism fight, covering skill timing, elite pathing, potion planning, and safer deckbuilding after v0.106.0.
A practical Ironclad exhaust build guide for Slay the Spire 2 covering Ashen Strike scaling, Corruption cycling, and how to turn card removal into your win condition.
A practical Necrobinder Doom build guide for Slay the Spire 2 covering Doom mechanics, Osty summons, instant-kill thresholds, and how to bypass enemy defenses entirely.
A practical Silent shiv build guide for Slay the Spire 2 covering blade generation, Accuracy scaling, Knife Trap finishers, and Sly discard synergy.
A practical Act 1 route planning checklist for choosing fights, elites, shops, campfires, and safer paths in Slay the Spire 2.
A practical Act 2 survival guide covering defensive upgrades, route choices, scaling, potions, shops, and how to stop losing after a strong Act 1.
Learn how to prepare an Act 3 deck with enough scaling, defense, draw, and consistency to finish long fights instead of stalling out.

A beginner-friendly guide to early card picks, covering damage, block, scaling, utility, and when skipping a reward is better than adding a card.
A beginner potion guide explaining when to use potions, which potion effects are easiest to value, and why hoarding potions loses runs.
A beginner-friendly relic guide explaining which relic effects are easiest to use, when to value consistency, and how to avoid risky relic picks.
A beginner-focused character choice guide explaining how to pick a starter character by clarity, defense, damage, scaling, and learning value.
A boss preparation checklist for judging damage, block, scaling, potions, upgrades, and route choices before major fights.
Learn when to remove starter cards, how removal improves consistency, and when buying cards or relics matters more than deleting weak cards.
A practical guide to card draw and energy, explaining why strong decks need both consistency and enough resources to play their best hands.
A practical relic tier list framework for beginners, ranking relic effects by consistency, route impact, shop value, and ease of use.
A shop decision guide for choosing between relics and card removal in Slay the Spire 2, with clear examples for beginner and mid-run decks.
A practical campfire guide explaining when to rest, when to upgrade, and how to judge health, elites, bosses, and deck power.
A deck size guide explaining when small decks are stronger, when large decks are safer, and how beginners should think about consistency.